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Original article title

Impacts of mutation accumulation and order on tumor initiation revealed by engineered murine colorectal cancer organoids.

RESEARCHElife·

Abstract excerpt

“Collectively, our study reveals a critical role of ordered mutation accumulation in CRC initiation, an insight that may hold clinical relevance.”

Keep in mind

Preclinical · not proven in patients.

Read source / abstract ↗

pubmed.ncbi.nlm.nih.gov · Full-text access depends on the publisher.

The excerpt is quoted from source text. The original title is preserved above.

This is a reading aid. Follow the source for methods, limitations, corrections, and clinical context.