• IFNAR1 stabilization sustains CD8 + T cell persistence in IFN-high colorectal cancer liver metastases.

  Research · assess methods and limitations

  RESEARCHSci Adv·Nov 4, 2026Basic science
• A mechanistic pharmacokinetic-patient-derived organoid (PK-PDO) framework for comparing oxaliplatin HIPEC regimens in peritoneal metastases of colorectal cancer.

  Preclinical · not proven in patients

  RESEARCHEur J Pharm Sci·Nov 3, 2026
• Fast-Food Consumption Frequency, Residential Proximity to Fast-Food Restaurants and Colorectal Cancer Incidence: A Clinical Case-Control Study.

  Research · assess methods and limitations

  RESEARCHNutr Cancer·Nov 3, 2026
• Impacts of mutation accumulation and order on tumor initiation revealed by engineered murine colorectal cancer organoids.

  Preclinical · not proven in patients

  RESEARCHElife·Nov 3, 2026
• Making sense of TILs: recommendations for morphological assessment of tumour-infiltrating lymphocytes in colorectal carcinoma: a report on behalf of the International Immuno-Oncology Biomarker Working Group.

  Review

  RESEARCHHistopathology·Nov 3, 2026Guideline-related
  Review

  Sur D, Lang-Schwarz C, van Herpe F, Rasschaert G, Weeda YA, Littlefield N, Gu Q, Li N, Alexandros H, Hida AI, Bhalla A, Khramtsov AI, Ehinger A, Tanaka A, Acs B, Steen S, Ercan …

  Abstract / publisher access may vary
• NaB-induced inhibition of HDAC4 and TUG1: a novel strategy for reversing oxaliplatin resistance in colorectal cancer.

  Research · assess methods and limitations

  RESEARCHBMC Cancer·Nov 3, 2026
• Opportunistic Salpingectomy During Colorectal Surgery: A Missed Opportunity?

  Research · assess methods and limitations

  RESEARCHDis Colon Rectum·Nov 3, 2026
• Pectolinarigenin suppresses colorectal cancer progression through metabolism-associated signaling.

  Research · assess methods and limitations

  RESEARCHMol Biol Rep·Nov 3, 2026
• Surgeon-Level Value Measurement in Colectomy: Independent Domains of Cost, Efficiency, Conversion, and Outcomes.

  Observational · association, not causation

  RESEARCHDis Colon Rectum·Nov 3, 2026
• A patient-derived organ-on-a-chip platform for predicting chemotherapy response in locally advanced colorectal cancer.

  Preliminary laboratory platform with small clinical follow-up

  RESEARCHBioeng Transl Med·Nov 2, 2026
• Applying Geographic and Demographic Data to Explore Colorectal Cancer Risk Among Rural Texas Counties.

  Research · assess methods and limitations

  RESEARCHAm Surg·Nov 2, 2026
• ASO Visual Abstract: Impact of Systematic Discontinuation of Mitomycin C HIPEC for Colorectal Peritoneal Metastases on Oncologic Outcomes-A Propensity Score Matched Analysis.

  Research · assess methods and limitations

  RESEARCHAnn Surg Oncol·Nov 2, 2026
• Autonomous Bowel Suturing Still Has a Long Clinical Road

  Narrative review; autonomy remains largely preclinical

  RESEARCHJ Surg Res·Nov 2, 2026New technology
• Chemoprotective effect of pinoresinol diglucoside against 1,2-dimethylhydrazine-induced colorectal cancer through regulation of nuclear factor-kappa B/inducible nitric oxide synthase/cyclooxygenase-2 signaling and gut dysbiosis.

  Research · assess methods and limitations

  RESEARCHIndian J Pharmacol·Nov 2, 2026
• Circulating Tumor DNA and Cell-Free DNA as Candidate Biomarkers After Image-Guided Locoregional Therapy in Hepatocellular Carcinoma and Colorectal Liver Metastases: A Systematic Review.

  Evidence synthesis

  RESEARCHJ Vasc Interv Radiol·Nov 2, 2026Evidence update
• Estimating the clinical benefit of metastases resection in liver-limited metastatic colorectal cancer: an IPD-based pooled analysis of nine randomized trials.

  Pooled trial data; surgery itself was not randomized

  RESEARCHESMO Open·Nov 2, 2026Evidence update
• Exploring the Learning Curve of Intracorporeal Anastomosis in Minimally Invasive Right and Extended Right Colectomy: A Systematic Review.

  Evidence synthesis

  RESEARCHANZ J Surg·Nov 2, 2026Evidence update
  Review

  Chan KS, Oh SL, Ip BWK, On JWJ, Mantoo SK, Lee YZ.

  Abstract / publisher access may vary
• Integrated multi-omics and experimental evidence implicate DVL3-associated Wnt/β-catenin signaling in PFHxS-related colorectal cancer progression.

  Research · assess methods and limitations

  RESEARCHEcotoxicol Environ Saf·Nov 2, 2026
• Local Therapy of Metastases in Colorectal Cancer: Utilization and Survival in a Nationwide Population.

  Research · assess methods and limitations

  RESEARCHJCO Oncol Pract·Nov 2, 2026Practice relevance
• Long-term outcomes of colorectal cancer after indocyanine green fluorescence-guided laparoscopic radical resection: a retrospective cohort study.

  Retrospective matched cohort; association, not causation

  RESEARCHSurg Endosc·Nov 2, 2026Practice relevance
• Sex and Menopausal Status Do Not Independently Predict Survival in Colorectal Liver Metastases.

  Research · assess methods and limitations

  RESEARCHAm Surg·Nov 2, 2026Practice relevance
• Textbook Outcomes Following Simultaneous Colorectal-Liver Resection for Synchronous Colorectal Liver Metastasis: A Combination-Level Analysis Using the ACS-NSQIP Database.

  Observational · association, not causation

  RESEARCHJ Gastrointest Surg·Nov 2, 2026
• The Modern Continuum of Care for Colorectal Liver Metastases: A Comprehensive Review.

  Review

  RESEARCHAm Surg·Nov 2, 2026
• XIAP induces inflammation and promotes colorectal cancer progression.

  Research · assess methods and limitations

  RESEARCHCell Death Dis·Nov 2, 2026
• Adjuvant mFOLFOXIRI after curative-intent resection of oligometastatic colorectal cancer: phase II FANTASTIC trial.

  Small nonrandomized phase II trial

  RESEARCHBJS Open·Nov 1, 2026Clinical trial

Selected for clinical relevance, new technology, guidelines, and interesting perspectives. Preliminary work is labeled; interest is not a quality rating. Eight headlines have reviewed AI-assisted rewrites; other titles appear as published.