• Synthetic Platelets Aim for Human Testing in 2027

  Perspective; preclinical technology, not established human benefit

  ARTICLEAmerican College of Surgeons·Nov 4, 2026Practice relevanceWorth a read
• Advocacy Training Prepares Surgeons to Influence Policy and Health

  Viewpoint; program description

  ARTICLEAmerican College of Surgeons·Nov 4, 2026Worth a read
• IFNAR1 stabilization sustains CD8 + T cell persistence in IFN-high colorectal cancer liver metastases.

  Research · assess methods and limitations

  RESEARCHSci Adv·Nov 4, 2026Basic science
• What Aviation Taught Me About Becoming a Better Surgeon

  Personal viewpoint

  ARTICLEAmerican College of Surgeons·Nov 4, 2026Practice relevanceWorth a read
• A mechanistic pharmacokinetic-patient-derived organoid (PK-PDO) framework for comparing oxaliplatin HIPEC regimens in peritoneal metastases of colorectal cancer.

  Preclinical · not proven in patients

  RESEARCHEur J Pharm Sci·Nov 3, 2026
  Journal article

  Namakshenas P, Helderman RFCPA, Ceelen W, Kok HP, Crezee J.

  Abstract / publisher access may vary
• Fast-Food Consumption Frequency, Residential Proximity to Fast-Food Restaurants and Colorectal Cancer Incidence: A Clinical Case-Control Study.

  Research · assess methods and limitations

  RESEARCHNutr Cancer·Nov 3, 2026
• Impacts of mutation accumulation and order on tumor initiation revealed by engineered murine colorectal cancer organoids.

  Preclinical · not proven in patients

  RESEARCHElife·Nov 3, 2026
• Making sense of TILs: recommendations for morphological assessment of tumour-infiltrating lymphocytes in colorectal carcinoma: a report on behalf of the International Immuno-Oncology Biomarker Working Group.

  Review

  RESEARCHHistopathology·Nov 3, 2026Guideline-related
• NaB-induced inhibition of HDAC4 and TUG1: a novel strategy for reversing oxaliplatin resistance in colorectal cancer.

  Research · assess methods and limitations

  RESEARCHBMC Cancer·Nov 3, 2026
• Opportunistic Salpingectomy During Colorectal Surgery: A Missed Opportunity?

  Research · assess methods and limitations

  RESEARCHDis Colon Rectum·Nov 3, 2026
• Pectolinarigenin suppresses colorectal cancer progression through metabolism-associated signaling.

  Research · assess methods and limitations

  RESEARCHMol Biol Rep·Nov 3, 2026
• Surgeon-Level Value Measurement in Colectomy: Independent Domains of Cost, Efficiency, Conversion, and Outcomes.

  Observational · association, not causation

  RESEARCHDis Colon Rectum·Nov 3, 2026
• A patient-derived organ-on-a-chip platform for predicting chemotherapy response in locally advanced colorectal cancer.

  Preliminary laboratory platform with small clinical follow-up

  RESEARCHBioeng Transl Med·Nov 2, 2026
• Applying Geographic and Demographic Data to Explore Colorectal Cancer Risk Among Rural Texas Counties.

  Research · assess methods and limitations

  RESEARCHAm Surg·Nov 2, 2026
• ASO Visual Abstract: Impact of Systematic Discontinuation of Mitomycin C HIPEC for Colorectal Peritoneal Metastases on Oncologic Outcomes-A Propensity Score Matched Analysis.

  Research · assess methods and limitations

  RESEARCHAnn Surg Oncol·Nov 2, 2026
• Autonomous Bowel Suturing Still Has a Long Clinical Road

  Narrative review; autonomy remains largely preclinical

  RESEARCHJ Surg Res·Nov 2, 2026New technology
• Chemoprotective effect of pinoresinol diglucoside against 1,2-dimethylhydrazine-induced colorectal cancer through regulation of nuclear factor-kappa B/inducible nitric oxide synthase/cyclooxygenase-2 signaling and gut dysbiosis.

  Research · assess methods and limitations

  RESEARCHIndian J Pharmacol·Nov 2, 2026
  Journal article

  Hong H, Tian Z, Gao B.

  Abstract / publisher access may vary
• Circulating Tumor DNA and Cell-Free DNA as Candidate Biomarkers After Image-Guided Locoregional Therapy in Hepatocellular Carcinoma and Colorectal Liver Metastases: A Systematic Review.

  Evidence synthesis

  RESEARCHJ Vasc Interv Radiol·Nov 2, 2026Evidence update
• Estimating the clinical benefit of metastases resection in liver-limited metastatic colorectal cancer: an IPD-based pooled analysis of nine randomized trials.

  Pooled trial data; surgery itself was not randomized

  RESEARCHESMO Open·Nov 2, 2026Evidence update
• Exploring the Learning Curve of Intracorporeal Anastomosis in Minimally Invasive Right and Extended Right Colectomy: A Systematic Review.

  Evidence synthesis

  RESEARCHANZ J Surg·Nov 2, 2026Evidence update
• Integrated multi-omics and experimental evidence implicate DVL3-associated Wnt/β-catenin signaling in PFHxS-related colorectal cancer progression.

  Research · assess methods and limitations

  RESEARCHEcotoxicol Environ Saf·Nov 2, 2026
• Local Therapy of Metastases in Colorectal Cancer: Utilization and Survival in a Nationwide Population.

  Research · assess methods and limitations

  RESEARCHJCO Oncol Pract·Nov 2, 2026Practice relevance
• Long-term outcomes of colorectal cancer after indocyanine green fluorescence-guided laparoscopic radical resection: a retrospective cohort study.

  Retrospective matched cohort; association, not causation

  RESEARCHSurg Endosc·Nov 2, 2026Practice relevance
• Sex and Menopausal Status Do Not Independently Predict Survival in Colorectal Liver Metastases.

  Research · assess methods and limitations

  RESEARCHAm Surg·Nov 2, 2026Practice relevance
• Textbook Outcomes Following Simultaneous Colorectal-Liver Resection for Synchronous Colorectal Liver Metastasis: A Combination-Level Analysis Using the ACS-NSQIP Database.

  Observational · association, not causation

  RESEARCHJ Gastrointest Surg·Nov 2, 2026

Selected for clinical relevance, new technology, guidelines, and interesting perspectives. Preliminary work is labeled; interest is not a quality rating. Eight headlines have reviewed AI-assisted rewrites; other titles appear as published.